Not known Details About indazole drug design
In vivo, 167 improved motor capabilities in MPTP-induced Parkinson’s mice, restored dopamine degrees in the striatum, and decreased oxidative stress and neuroinflammation by cutting down the activation of microglia and astrocytes. The neuroprotective results had been achieved by upregulating antioxidative enzymes which include SOD2, NRF2, and NQO